Cord Blood Stem Cells – Diseases Treated

Over 80 life-threatening diseases and disorders are currently being treated using stem cells from cord blood.  Cord blood stem cells are a better alternative to bone marrow stem cells in transplants for many reasons. Some reasons include the low risk of graft vs host disease when using cord blood and the fact that cord blood does not require a perfect HLA-match.  Here are some of the diseases and disorders stem cells from cord blood can be used in therapy to treat:

Acute Leukemias
Acute Lymphoblastic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Biphenotypic Leukemia
Acute Undifferentiated Leukemia

Chronic Leukemias
Chronic Myelogenous Leukemia (CML)
Chronic Lymphocytic Leukemia (CLL)
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)

Myelodysplastic Syndromes
Refractory Anemia (RA)
Refractory Anemia with Ringed Sideroblasts (RARS)
Refractory Anemia with Excess Blasts (RAEB)
Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
Chronic Myelomonocytic Leukemia (CMML)

Stem Cell Disorders
Aplastic Anemia (Severe)
Fanconi Anemia
Paroxysmal Nocturnal Hemoglobinuria (PNH)

Myeloproliferative Disorders
Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (myelofibrosis)
Polycythemia Vera
Essential Thrombocythemia

Lymphoproliferative Disorders
Non-Hodgkin’s Lymphoma
Hodgkin’s Disease
Prolymphocytic Leukemia

Phagocyte Disorders
Chediak-Higashi Syndrome
Chronic Granulomatous Disease
Neutrophil Actin Deficiency
Reticular Dysgenesis

Liposomal Storage Diseases
Mucopolysaccharidoses (MPS)
Hurler’s Syndrome (MPS-IH)
Scheie Syndrome (MPS-IS)
Hunter’s Syndrome (MPS-II)
Sanfilippo Syndrome (MPS-III)
Morquio Syndrome (MPS-IV)
Maroteaux-Lamy Syndrome (MPS-VI)
Sly Syndrome,Beta-Glucuronidase Deficiency (MPS-VII)
Adrenoleukodystrophy Mucolipidosis II (I-cell Disease)
Krabbe Disease
Gaucher’s Disease
Niemann-Pick Disease
Wolman Disease
Metachromatic Leukodystrophy

Histiocytic Disorders
Familial Erythrophagocytic
Lymphohistiocytosis
Histiocytosis-X
Hemophagocytosis

Inherited Erythrocyte Abnormalities
Beta Thalassemia
Major Pure Red Cell Aplasia
Sickle Cell Disease

Congenital (Inherited) Immune System Disorders
Ataxia-Telangiectasia
Kostmann Syndrome
Leukocyte Adhesion Deficiency
DiGeorge Syndrome
Bare Lymphocyte Syndrome
Omenn’s Syndrome
SCID Common Variable Immunodeficiency
Wiskott-Aldrich Syndrome
X-Linked Lymphoproliferative Disorder

Other Inherited Disorders
Lesch-Nyhan Syndrome
Cartilage-Hair Hypoplasia
Glanzmann Thrombasthenia
Osteopetrosis

Inherited Platelet Abnormalities
Amegakaryocytosis / Congenital Thrombocytopenia

Plasma Cell Disorders
Multiple Myeloma Plasma Cell Leukemia
Waldenstrom’s Macroglobulinemia

Other Malignancies
Breast Cancer
Ewing Sarcoma
Neuroblastoma
Renal Cell Carcinoma

Disclaimer: AlphaCord does not endorse or make recommendations with respect to research, medications, or treatment. All information provided is for informational purposes only and does not replace professional medical advice.